Selected Manuscripts & Publications
1.YOTSU-YAMASHITA, M., Y.H. KIM, S.C. DUDLEY, Jr., G. CHOUDHARY, A. PFANHL, Y. OSHIMA, J.W. DALY. The Structure of Zetekitoxin AB, a Novel Saxitoxin Analog from the Panamanian Golden Frog Atelopus zeteki: A Potent Sodium-Channel Blocker. (2004). Proc.Nat'l.Acad.Sci USA, vol. 101, 4346-4351. (Adobe PDF File Size: 503 KB)

2. ZAFARI, A.M., S.K. ZARTER, V. HEGGEN, P. WILSON, R.A. TAYLOR, K. REDDY, A.G. BACKSCHEIDER, S.C. DUDLEY, Jr. A Program Encouraging Early Defibrillation Results in Improved In-Hospital Resuscitation Efficacy. (2004). J. Am. Coll. Cardiol. 44:846-852. (Adobe PDF File Size: 182 KB)

3. XIAO, H.D., S. FUCHS, D.J. CAMPBELL, W. LEWIS, S.C. DUDLEY, Jr., V.S. KASI, B.D. HOIT, G. KESHELAVA, H. ZHAO, M.R. CAMPECCHI, K.E. BERNSTEIN. Mice with cardiac restricted angiotensin converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia and sudden death. (2004). Am. J. Pathol. 165:1019-1032. (Adobe PDF File Size: 1.1 MB)

4. DIAMANDOPOULOS, L., S.C. DUDLEY, Jr. Atrial Fibrillation: Are We Treating the Right Disease?. (2003). Cardiovascular Reviews & Reports vol. 24, 514-519.

5 . ZHANG, Y.M., L. SHANG, C. HARTZELL, M. NARLOW, L. CRIBBS, S.C. DUDLEY, Jr. Characterization and Regulation of T-type Ca2+ Channels in Embryonic Stem Cell-Derived Cardiomyocytes. (2003). Am. J. Physiol. vol. 285, H2770-2779. (Adobe PDF File Size: 460 KB)

6 . LYNN, M., D. KLEINHENZ, H. THORSON, W. KANNER, S. DUDLEY, C.M. HART. Fatty acids differentially modulate insulin-stimulated endothelial nitric oxide production by an Akt-independent pathway. (2004). Journal of Investigative Medicine. vol. 52, 129-136. (Adobe PDF File Size: 334 KB)

7 . SOLIMAN, G.M.,S.C. DUDLEY, Jr,. Risk Stratification and Treatment for Sudden Cardiac Death. (2003). Hospital Physician vol. 8, 2-12. (Adobe PDF File Size: 1.7 MB)

8 . S. DIKALOV, S.M. HOLLAND, J. HWANG, H. JO, S.C. DUDLEY, Jr., D.G. HARRISON. 2002. NAD(P)H Oxidase-Derived Hydrogen Peroxide Mediates Endothelial Nitric Oxide Production in Response to Angiotensin II. J. Biol. Chem. 277:48311-48317. (Adobe PDF File Size: 334 KB)

9 . CAI, H.,Z. LI, M.E. DAVIS, W. KANNER, D.G. HARRISON,S.C. DUDLEY, Jr. Akt-Dependent Phosphorylation of Serine 1179 and MEK/ERK1/2 Cooperatively Mediate Activation of the Endothelial Nitric Oxide Synthase by Hydrogen Peroxide. (2003). Mol. Pharmacol. vol. 63, 325-333. (Adobe PDF File Size: 323 KB)

10 . CHOUDHARY, G. & S.C. DUDLEY, Jr. 2002. Heart Failure, Oxidative Stress and Ion Channel Modulation. Congestive Heart Failure. 8:148-155. (Adobe PDF File Size: 712 KB)

11. CHOUDHARY, G., L. SHANG, X. LI, S.C. DUDLEY, Jr. 2002. Energetic Localization of Saxitoxin in its Channel Binding Site. Biophys. J. 83:912-919. (Adobe PDF File Size: 325 KB)

12. ZHANG, Y.M., C. HARTZELL, M. NARLOW, S.C. DUDLEY, Jr. 2002. Stem Cell Derived Cardiomyocytes Demonstrate Arrhythmic Potential. Circulation. 106:1294-1299. (Adobe PDF File Size: 117 KB)

13. HILBER, K., W. SANDTNER, O. KUDLACEK, B. SCHREINER, I. GLAASER, W. SCHÜTZ, H.A. FOZZARD, S.C. DUDLEY, H. TODT. 2002. Interaction between Fast and Ultra-Slow Inactivation in the Voltage-Gated Sodium Channel: Does the Inactivation Gate Stabilize the Channel Structure? J. Biol. Chem. 277:37105-37115. (Adobe PDF File Size: 222 KB)

14. CAI, H., Z.M. LI, A. GOETTE, F. MERA, C. HONEYCUTT, K. FERERIK, J.N. WILCOX, S.C. DUDLEY, Jr., D.G. HARRISON, J.J. LANGBERG. 2002. Downregulation of Nitric Oxide Synthase Expression and Nitric Oxide Production in Atrial Fibrillation: Potential Mechanisms of Atrial Thrombosis and Stroke. Circulation. 106:2854-2858. (Adobe PDF File Size: 440 KB)

15. CHOUDHARY, G., M. YOTSU-YAMASHITA, L. SHANG, T. YASUMOTO, S.C. DUDLEY, Jr. 2002. Interactions of the C-11 Hydroxyl of Tetrodotoxin with the Sodium Channel Outer Vestibule. Biophys. J. 84:287-294. (Adobe PDF File Size: 200 KB)

16. HANNES, T., S.C. DUDLEY, Jr., J.W. KYLE, R.J. FRENCH, H.A. FOZZARD. 1999. Ultra-Slow Inactivation in µ1 Na+ Channels Is Produced by a Structural Rearrangement of the Outer Vestibule. Biophys. J. 76:1335-1345. (Adobe PDF File Size: 128 KB)

17. LI, R.A., I.L. ENNIS, R.J. FRENCH, S.C. DUDLEY, Jr., G.F. TOMASELLI, E. MARBAN. 2001. Clockwise Domain Arrangement of the Sodium Channel Revealed by µ-Conotoxin (GIIIA) Docking Orientation. J. Biol. Chem. 276:11072-11077. (Adobe PDF File Size: 791 KB)

18. From Stem Cells to Heart Cells. Ivanhoe's Medical Breakthroughs, Retrieved November 6, 2001, from http://www.ivanhoe.com/stream/fromstemcellstoheartcells.shtml (Adobe PDF File Size: 163 KB)