Publications

Peer-reviewed publications

A Freire, GE Umpierrez, B Afessa, KA Latif, L Bridges, AE Kitabchi. Predictors of ICU and Hospital length of stay in diabetic ketoacidosis. Critical Care Journal, 17:207-211, 2002.

AE Kitabchi, FB Stentz, GE Umpierrez. Diabetic ketoacidosis induces in vivo activation of human T-lymphocytes. Biochem Biophys Res Commun. 5;315(2):404-7, 2004.

AE Kitabchi, GE Umpierrez, MB Murphy, EJ Barret, RA Kreisberg, JI Malone, BM Wall. Hyperglycemic Crises in Diabetes. Diabetes Care 27:Suppl 1:S94-102, Jan 2004.

AE Kitabchi, GE Umpierrez, MB Murphy, EJ Barret, RA Kreisberg, JI Malone, BM Wall. Hyperglycemic Crises in Patients with Diabetes Mellitus. Diabetes Care Suppl 1:S109-17, 2003. 2003

AE Kitabchi, GE Umpierrez, MB Murphy, RA Kreisberg. Revised American Diabetes Position Statement, Hyperglycemic Crises in Patients with Diabetes Mellitus. Diabetes Care, 29:2739-2748, 2006.

AE Kitabchi, GE Umpierrez, MB Murphy. Diabetic Ketoacidosis and hyperglycemic hyperosmolar state. International Textbook of Diabetes Mellitus, 2003.

AE Kitabchi, GE Umpierrez. Changes in serum leptin in lean and obese subjects with acute hyperglycemic crises. J Clin Endocrinol Metabol 88:2593-2596, 2003.

AX Freire, GE Umpierrez, L Bridges, D Kuhl, AE Kitabchi. Admission hyperglycemia and other risk factors as predictors of hospital mortality in a medical ICU population. Chest, 128;3109-3116, 2005

Barnes CS, Ziemer DC, Miller CD, Doyle JP, Watkins C Jr., Cook CB, Gallina DL, El-Kebbi IM, Branch WT Jr., Phillips LS. There is little time for diabetes management in the primary care setting. Diabetes Educator 2004; 30(1): 126-135.

Barnes, C. S., Ziemer, D.C., Miller, C.D., Doyle, J.P., Watkins, C. Jr., Cook, C.B., Gallina, D.L., El-Kebbi, I.M., Branch, W.T. Jr., Phillips, L.S. There is little time for diabetes management in the primary care setting (IPCAAD 4). The Diabetes Educator 30: 126-135, 2004.

D Smiley, GE Umpierrez, Perioperative management in diabetes mellitus. South Med J. 99(6):580-9, 2006.

El-Kebbi IM, Ziemer DC, Cook CB, Gallina DL, Barnes CS, Phillips LS. Utility of casual post-prandial glucose levels in Type 2 diabetes management. Diabetes Care 2004; 27: 335-339.

El-Kebbi IM, Ziemer DC, Cook CB, Gallina DL, Barnes CS, Phillips LS. Utility of casual postprandial glucose levels in Type 2 diabetes management. Diabetes Care 2004; 27:335-339.

Fisk DM, Hayes RP, Barnes CS, Cook CB. Physician assistant students and diabetes: Evaluation of attitudes and beliefs. The Diabetes Educator 2001; 27(1): 111-117.

GE Umpierrez, AE Kitabchi. Diabetic Ketoacidosis: Risk Factors and Management Strategies. Treat Endocrinol 2:95-108, 2003.

GE Umpierrez, AE Kitabchi. Hyperglycemia: An independent marker of in-hospital mortality in patients with undiagnosed diabetes. J Clin Endocrinol Metabol 88:1402, 2003.

GE Umpierrez, AE Kitabchi. ICU Care for Patients with Diabetes. Current Opinions Endocrinol 11:75-81, 2004.

GE Umpierrez, AE Kitabchi. Treatment of Diabetic Ketoacidosis with Subcutaneous Insulin Lispro. Am J Med 96-97, 2005.

GE Umpierrez, AX Freire. Abdominal pain in patients with hyperglycemic crises. J Critical Care, 17:63-67,2002.

GE Umpierrez, D Smiley, A Gosmanov, D Thomason. Ketosis-Prone Type 2 Diabetes: The Effect of Hyperglycemia on -cell function and Insulin Signaling. Endocrine Practice, in press, 2007.

GE Umpierrez, D Smiley, A Palacio. The Sliding Scale Insulin Use: Myth or Insanity? Am J Med, in press, 2007

GE Umpierrez, D Smiley, AE Kitabchi. Ketosis-prone diabetes mellitus. Annals Internal Medicine 144: 350-357, 2006

GE Umpierrez, D Smiley. Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar Syndrome. Section II Complications, In Clinical Diabetes: Translating Research into Practice. Vivian Fonseca, ed, 101-118, 2006.

GE Umpierrez, G Maynard. Glycemic Chaos (not glycemic control) stills the rule for inpatient care. How do we stop the insanity? J Hospital Medicine, 1:143-144, 2006.

GE Umpierrez, JF Fisher. Diabetes Ketoacidosis and Hyperosmolar Hyperglycemic State. In: Conn's Current Therapy. Rakel RE, ed. Elsevier Science (USA), Philadelphia, 636-642, 2003.

GE Umpierrez, K Latif, J Stoever, R Cuervo, L Park, AX Freire, AE Kitabchi. Efficacy of Subcutaneous Insulin Lispro Versus Continuous Intravenous Regular Insulin for Treatment of Diabetic Ketoacidosis. Am J Med, 117:291-296, 2004.

GE Umpierrez, K Latif, R Cuervo, A Karabell, AE Kitabchi. Treatment of diabetic ketoacidosis with subcutaneous insulin aspart. Diabetes Care 27:1873-1878, 2004.

GE Umpierrez, KA Latif, MB Murphy, F Stentz, HC Lambeth, A Bush, AE Kitabchi. Thyroid dysfunction in patients with type 1 diabetes: A longitudinal study. Diabetes Care 26: 1181-1185, 2003.

GE Umpierrez, M Issa, A Vlajnic. Glimepiride Versus Pioglitazone Combination Therapy in Subjects with Type 2 Diabetes Inadequately Controlled on Metformin Monotherapy. Current Medical Research and Opinion 22: 751-759, 2006

GE Umpierrez, MB Murphy, AE Kitabchi. Diabetic ketoacidosis and hyperglycemic hyperosmolar syndrome. Diabetes Spectrum, 15:2836, 2002.

GE Umpierrez, S Dagogo-Jack. Role of Thiazolidinediones in the Management of Type 2 diabetes: Focus on Ethnic Minority Populations. Ethnicity & Dis. Vol.16 (No. 1): 51-57, 2006

GE Umpierrez, SD Isaacs, N Bazargan, X You, L Taylor, AE Kitabchi. Hyperglycemia: An independent marker of in-hospital mortality in patients with undiagnosed diabetes. J Clin Endocrinol Metabol, 87:978-982, 2002.

GE Umpierrez. Euthyroid Sick Syndrome. Southern Medical Journal. 96:506-513, 2002.

GE Umpierrez. Ketosis-Prone Type 2 Diabetes mellitus: Time to Revise the Classification of Diabetes. Diabetes Care 29: 2755-2757, 2006

Gosmanov AR, GE Umpierrez, Karabell AH, Cuervo R, Thomason DB. Impaired insulin-stimulated Akt-2 Phosphorylation in muscle of obese patients with atypical diabetes. Am J Physiol Endocrinol Metab 287:E8-E15, 2004.

K Latif, AX Freire, GE Umpierrez, M Qureshi, AE Kitabchi. The use of alkali therapy in severe diabetic ketoacidosis (DKA). Diabetes Care 25:2113-2114, 2002.

M Doss, GE Umpierrez. Perioperative management of diabetic patients. In Textbook of the Society of Hospital Medicine, in press

ML Hartman, BJ Crowe, BMK Biller, KKY Ho, DR Clemmons, JJ Chipman on behalf of the HypoCCS Advisory Board and the U.S. HypoCCS Study Group. Which Patients Do Not Require a GH Stimulation Test for the Diagnosis of Adult GH Deficiency? J Clin Endocrinol Metabol. 87: 2477-2485, 2002.

MS Schneider, GE Umpierrez, TS Ivester, WC Mabie, RD Ramsey, KA Bennett. Maternal and fetal outcomes following hospitalization for diabetic ketoacidosis. Diabetes Care, 26:958, 2003.

Miller CD, Barnes CS, Phillips LS, Ziemer DC, Gallina DL, Cook CB, El-Kebbi IM. Same-day HbA1c availability improves diabetes clinical decision-making in an urban primary care clinic. Diabetes Care 2001; 26(4): 1158-63.

Miller CD. Ziemer DC. Kolm P. El-Kebbi IM. Cook CB. Gallina DL. Doyle JP. Barnes CS. Phillips LS. Use of a glucose algorithm to direct diabetes therapy improves A1C outcomes and defines an approach to assess provider behavior. Diabetes Educator. 32(4):533-45, 2006 Jul-Aug.

Miller CdD, Barnes CS, Phillips LS, Ziemer DC, Gallina DL, Cook CB, Maryman SD, El-Kebbi IM. Rapid a1c availability improves clinical decision-making in an urban primary care clinic. Diabetes Care 2003; 26(4): 1158-63.

Miller, C.D., Ziemer, D.C., Doyle, J.P., Cook, C.B., El-Kebbi, I.M., Gallina, D.L., Watkins, C. Jr., Barnes, C.S., Walker, G.D., Lyles, R.H., Hertzberg, V.S., McClellan, W.M., Branch, W.T. Jr., Phillips, L.S. Diabetes management by residents in training at a municipal hospital primary care site (IPCAAD 2). 2005. Ethnicity & Disease. 15(2):173-8.

P Cantey, GE Umpierrez. Diabetic Ketoacidosis. In Textbook of the Society of Hospital Medicine, in press

P Cantey, GE Umpierrez. Inpatient hyperglycemia. In Textbook of the Society of Hospital Medicine, in press

P Velasquez-Mieyer, GE Umpierrez, RH Lustig, AK Cashion, P Cowan, M Christensen, KA Spencer, GA Burghen. Race affects on Insulin and GLP-1 secretion and response to sandostatin-LAR in obese adults. Int J Obes Relat Metab Disord. 28(2):330-3, 2004.

P Velasquez-Mieyer, P Cowan, GE Umpierrez, RH Lustig, AK Cashion, GA Burghen. Racial differences in insulin and glucagon-like peptide 1 (GLP-1) secretion during oral glucose tolerance test in obese non-diabetic subjects. International J Obesity, 27:1359-1364, 2003.

Phillips LS, Branch WT Jr., Cook CB, Doyle JP, El-Kebbi IM, Gallina DL, Miller CD, Ziemer DC, Barnes CS. Clinical inertia. Annals of Internal Medicine 2001; 135: 825-834.

Phillips LS, Cook CB, El-Kebbi IM, Gallina DL, Ziemer DC, Miller CD, Doyle JP, Hayes RP, Ballard DJ, Barnes CS, Slocum W, Hertzberg VS, Lyles RH, McClellan WM, Branch WT Jr. The Improving Primary Care of African Americans with Diabetes (IPCAAD 1) Project: Rationale and Design. Controlled Clinical Trials 2002; 23: 554-569.

Phillips, L.S., Ziemer, D.C., Doyle, J.P., Barnes, C.S., Kolm, P, Branch, W.T., Caudle, J.M., Cook, C.B., Dunbar, V.G., El-Kebbi, I.M., Gallina, D.L., Hayes, R.P., Miller, C.D., Rhee, M.K., Thompson, D.M., Watkins, C. An Endocrinologist-Supported Intervention Aimed at Providers Improves Diabetes Management in a Primary Care Site: Improving Primary Care of African Americans with Diabetes (IPCAAD 7). 2005. Diabetes Care 28(10): 2352-2360.

Rhee MK, Slocum WP, Ziemer DC, Culler SD, Cook CB, El-Kebbi IM, Gallina DL, Barnes CS, Phillips LS. Patient adherence improves glycemic control. The Diabetes Educator 2005; 31: 240-250.

Stentz F, GE Umpierrez, R Cuervo, AE Kitabchi. Proinflammatory Cytokines, Markers of Cardiovascular Risks, Oxidative Stress, and Lipid Peroxidation in Patients with Hyperglycemic Crises. Diabetes 53:2079-2086, 2004.

Ziemer DC. Miller CD. Rhee MK. Doyle JP. Watkins C Jr. Cook CB. Gallina DL. El-Kebbi IM. Barnes CS. Dunbar VG. Branch WT Jr. Phillips LS. Clinical inertia contributes to poor diabetes control in a primary care setting (IPCAAD 3). 2005. Diabetes Educator. 31(4):564-71.

Ziemer, D.C., Doyle, J.P., Barnes, C. S., Branch, W.T. Jr., Cook, C.B., El-Kebbi, I.M., Gallina, D.L., Kolm, P., Rhee, M.K., Phillips, L.S. An intervention to overcome clinical inertia and improve diabetes control in a primary care setting. IPCAAD 8. Arch Int Med 166: 507-513, 2006.

Published abstracts

Admission Blood Glucose Level and Mortality Risk in Medical ICU. GE Umpierrez, AX Freire, L Bridges, AE Kitabchi. Endocrine Society's 86th Annual Meeting, 2004.

Agrawal, V, Korb, P, Cole, R, Barnes, C.S., Rhee, M.K., Ziemer, D.C., Caudle, J.M., Kehdkar, S., Phillips, L.S.. Patients who know the A1c goal have better glycemic control. American Diabetes Association, San Diego, CA, June 2005.

Barnes, C.S., Phillips, L.S., Caudle, J.M., Tsui, C.W., Watkins, N., Ziemer, D.C.. Patient Perception of their level of glycemic control should aid patient empowrment intervention. American Diabetes Association, Washington, D.C., June 2006.

Barnes, C.S., Phillips, L.S., Caudle, J.M., Tsui, C.W., Watkins, N., Ziemer, D.C.. Patient Perception of their level of glycemic control should aid patient empowrment intervention. American Diabetes Association, Washington, D.C., June 2006.

Barriers to diabetes care in Latino/Hispanic patients. A Palacio , D Smiley, GE Umpierrez. American Federation of Medical Research, Southern Society Meeting, 2006

Basal/Bolus regimen with Glargine and Glulisine versus Sliding Scale Regular Insulin In the Management of Noncritically Ill Patients With Type 2 Diabetes. GE Umpierrez, A Zisman, D Smiley, LM Prieto, M Ceron, A Palacio. American Diabetes Association, 67th Scientific Sessions, 2007.

Beta-Cell Function in Patients with Ketosis-Prone Type 2 Diabetes (KPD) and Recurrent Episodes of Diabetic Ketoacidosis. GE Umpierrez, AE Kitabchi. , American Diabetes Association, 64th Scientific Sessions, 2004.

Beta-cell function and muscle insulin signaling in obese African Americans with atypical diabetes. A Gosmanov, GE Umpierrez, R Cuervo, A Karabell, D Thomason. 1237-P, American Diabetes Association, 63rd Scientific Sessions, New Orleans, LA, 2003.

Cytokine Response In Lean and Obese Patients With Diabetic Ketoacidosis. K Latif, GE Umpierrez, F Stentz, B Culbreath, J Crisler, AE Kitabchi. 84th Annual Meeting of Endocrine Society, 2002.

Cytokine response in patients with diabetic ketoacidosis. GE Umpierrez, B Culbreath, J Crisler, F Stentz, A Kitabchi. 2002 Southern Regional Meetings, New Orleans, Louisiana, 2002.

Determinants of Progression Of Albuminuria In African-American Patients With Type 2 Diabetes. IM El-Kebbi, VG Dunbar, DC Ziemer, DD Smiley, CS Barnes, MK Rhee, JM Caudle, GE Umpierrez. American Diabetes Association, 66th Scientific Sessions, 2006.

Diabetes Care Barriers In Latino/Hispanic Patients. A Palacio, MK Rhee, DC Ziemer,

Diabetes Type 2 in elderly African Americans. M Rhee, D Ziemer, D Gallina, LS Phillips, GE Umpierrez. Endocrine Society's 86th Annual Meeting, 2004.

Diabetic Ketoacidosis During Pregnancy: Maternal and Fetal Outcomes. M Schneider, K Bennett, GE Umpierrez. Department of OB-GYN and Medicine, University of Tennessee, Memphis. 84th Annual Meeting of Endocrine Society, 2002.

Diabetic ketoacidosis during pregnancy in African American Women with type 2 diabetes. M Schneider, R Cuervo, A Karabell, GE Umpierrez. P2-254, presented Endocrine Society's 85th Annual Meeting, Philadelphia, 2003.

El Kebbi, I., Dunbar, V.G., Smiley, D., Barnes, C.S., Rhee, M.K., Caudle, J.M., Umpierrez, G.. Determnants of progression of albuminuria in African-American patients with Type 2 diabetes. American Diabetes Association, Washington, D.C., June 2006.

Factors Associated With Microalbuminuria In Resistant Hypertensive Type 2 Diabetics Undergoing Screening For Primary Hyperaldosteronism. G Baramidze, GE Umpierrez, A Chapman. 2007

Free Fatty Acid-Induced Acute Metabolic Syndrome. Dawn Smiley, Gonzalo Robalino, GE Umpierrez. European Association Study of Diabetes (EASD) Meeting, Athens, Greece, 2005.

Free Fatty Acid-Induced Hypertension And Acute Metabolic Syndrome In Obese African Americans. GE Umpierrez, Dawn Smiley, Gonzalo Robalino, Bobby Khan, Paul Kolm, Warren Davis, Virgil Brown, Lawrence Phillips, Atlanta, GA. American Diabetes Association, 65th Scientific Sessions, 2005.

Gestational diabetes mellitus in African Americans. M Schneider, R Cuervo, A Karabell, GE Umpierrez. 2460 PO, American Diabetes Association, 63rd Scientific Sessions, New Orleans, LA, 2003.

High Prevalence Of Primary Aldosteronism In Diabetic Patients With Resistant Hypertension. GE Umpierrez, P Cantey, D Smiley, D Temponi. American Diabetes Association, 66th Scientific Sessions, 2006.

High Prevalence of Primary Aldosteronism In Diabetic Patients With Resistant Hypertension. D Smiley, P Cantey, D Temponi, GE Umpierrez. Endocrine Society's 88th Annual Meeting, 2006.

Hyperthyroidism in end stage renal disease. N Qureshi, GE Umpierrez. PI-502, presented Endocrine Society's 85th Annual Meeting, Philadelphia, 2003.

In situ activation of T-lymphocytes in patients with diabetic ketoacidosis. FB Stenz, GE Umpierrez, R Cuervo, AE Kitabchi. P1271, American Diabetes Association, 63rd Scientific Sessions, New Orleans, LA, 2003.

Kebbi, I., Dunbar, V.G., Smiley, D., Barnes, C.S., Rhee, M.K., Caudle, J.M., Umpierrez, G.. Determnants of progression of albuminuria in African-American patients with Type 2 diabetes. American Diabetes Association, Washington, D.C., June 2006.

Ketosis-Prone Type 2 Diabetes Mellitus. D Smiley, GE Umpierrez. American Diabetes Association, 66th Scientific Sessions, 2006.

Ketosis-prone type 2 diabetes mellitus. D Smiley, GE Umpierrez, American Federation of Medical Research, Southern Society Meeting, 2006

Lack of Follow-Up Care: A Major Obstacle To Optimal Care In Latinos With Diabetes Guillermo Umpierrez, Dawn Smiley, Paul Kolm, Mary Rhee, David Ziemer, Daniel Gallina, Atlanta, Ga. American Diabetes Association, 65th Scientific Sessions, 2005.

Microarray Analysis of Proteins Involved in Signal Transduction And Apo-Ptosis in Skeletal Muscle of Patients With Ketosis-Prone Type 2 Diabetes Mellitus (KPDM). A.R. Gosmanov, D. Smiley, G. Robalino, G.E. Umpierrez, D.B. Thomason. American Federation Medical Research, 2007

Pathogenesis of -cell dysfunction in obese African-Americans with atypical diabetes. GE Umpierrez, R Cuervo, A Karabell, D Thomason. P2-253, presented Endocrine Society's 85th Annual Meeting, Philadelphia, 2003.

Phillips L, Kolm P, Ziemer DC, Cook CB, Gallina DL, Barnes CS, Doyle JP, Rhee MK, Mannepalli S. An endocrinologist-supported intervention improves provider behavior in the management of Type 2 diabetes in the primary care setting. American Diabetes Association, Orlando, June 2004.

Phillips L, Ziemer DC, Kolm GP, Gallina DL, Cook CB, Barnes CS, Doyle JP, Rhee MK. An endocrinologist-supported intervention aimed at overcoming clinical inertia improves diabetes management in a primary care site. American Diabetes Association, Orlando, June 2004.

Racial differences in insulin and glucagon-like peptide 1 (GLP-1) secretion during oral glucose tolerance test in obese non-diabetic subjects. P Velasquez-Mieyer, GE Umpierrez, RH Lustig, AK Cashion, P Cowan, GA Burghen. 62nd Scientific Session, American Diabetes Association, 2002.

Resistant Hypertension In Diabetes: Clinical Characteristics And Predictors Of Treatment Response. GE Umpierrez, CS Barnes, MK Rhee, JM Caudle, D Smiley, IM El-Kebbi, DC Ziemer. American Diabetes Association, 66th Scientific Sessions, 2006.

Safe and cost effective management of diabetic ketoacidosis with short-acting insulin analogs. GE Umpierrez, K Latif, R Cuervo, A Karabell, AE Kitabchi. P!-323, presented at Endocrine Society's 85th Annual Meeting, Philadelphia, 2003.

Subcutaneous Lispro Insulin In The Treatment of Diabetic Ketoacidosis. K Latif, GE Umpierrez, J Stoever, K Blaho, A Freire, L Parks, B Culbreath and AE Kitabchi. Submitted, 62nd Scientific Session, American Diabetes Association, 2002.

Subcutaneous aspart insulin: a safe and cost effective treatment of diabetic ketoacidosis. GE Umpierrez, K Latif, R Cuervo, A Karabell, AE Kitabchi. 584-P, American Diabetes Association, 63rd Scientific Sessions, New Orleans, LA, 2003.

The Effects Of Rosiglitazone On Free Fatty Acid-Induced Hypertension In Obese Subjects With Type 2 Diabetes. D Smiley, G Robalino, AE Kitabchi, F Stentz, GE Umpierrez. American Diabetes Association, 66th Scientific Sessions, 2006.

The Role of Glimepiride (GLIM) vs Pioglitazone (PIO) in Type 2 Diabetes Mellitus Subjects Not Responding Adequately to Metformin (MET) Monotherapy. GE Umpierrez, M Issa, Vlajnic A. American Diabetes Association, 64th Scientific Sessions, 2004 (submitted)

The use of alkali therapy in severe diabetic ketoacidosis (DKA). K Latif, A. Freire, GE Umpierrez, M Qureshi, A Kitabchi. Southern Regional Meetings, New Orleans, Louisiana, 2002.

Thirteen years of diabetes management in a municipal hospital system. DC Ziemer, MK Rhee, GE. Umpierrez, DL Gallina, LS Phillips. European Association Study of Diabetes (EASD) Meeting, Athens, Greece, 2005.

Thirteen years of diabetes management in a municipal hospital system. M Rhee, D Ziemer, LS Phillips, GE Umpierrez. American Federation of Medical Research, Southern Society Meeting, 2006

Umpierrez, G., Barnes, C.S. Rhee, M.K., Caudle, J.M., El Kebbi, I., Smiley, D., Ziemer, D.C.. Resistant hypertension in diabetes: Clinical characteristics and predictors of treatment response. American Diabetes Association, Washington, D.C., June 2006.

Umpierrez, G., Barnes, C.S. Rhee, M.K., Caudle, J.M., El Kebbi, I., Smiley, D., Ziemer, D.C.. Resistant hypertension in diabetes: Clinical characteristics and predictors of treatment response. American Diabetes Association, Washington, D.C., June 2006.

Underlying Mechanisms In The Pathogenesis Of Free Fatty Acid-Induced Hypertension In Obese African-Americans. D Smiley, G Robalino, AE Kitabchi, F Stentz, GE Umpierrez. American Diabetes Association, 66th Scientific Sessions, 2006.

Ziemer DC, Caudle JM, Barnes CS, Phillips L, Nesson CW, George CD. An endocrinologist supported intervention is cost saving in a public hospital system. American Diabetes Association, Orlando, June 2004.